Synthetic actives

Munapsys™ is a botulinum toxin-like peptide obtained by in silico design in collaboration with experts in neuroscience. It is the first cosmetic ingredient able to act both in the pre- and post-synaptic pathways of muscle contraction and in a new SNARE protein (Munc-18).

Munapsys™ mechanism is a real upgrade in the expression lines field, with proven efficacy compared with a benchmark combination even at a lower dose.

Sebaceous and sweat glands secretions and skin waste are metabolized or oxidized to Volatile Organic Compounds (VOCs) such as 2-nonenal and isovaleric acid. N_llscent™ immediately gets rid of the isovaleric acid smell from feet and armpits and of 2-nonenal from the neck and the belly.

Neøclair Pro™ is a primary antioxidant peptide which also acts as an antioxidant amplifier via NRF2/ARES pathway. Neøclair Pro™ offers 360° antipollution protection and repair, visibly lightening dark spots and improving brightening and aging and inflammaging signs.

Skinarch™ works on the four collagen families: fibrillar collagens, connecting and anchoring collagens, network-forming collagens and collagen-like membrane proteins. Moreover, its inclusive efficacy on skin architecture against wrinkles and sagging was proved in a mixed panel of volunteers with light-pigmented (phototype II-III) and dark-pigmented (phototype V-VI) skin.

Stellight™ is a smart creation of a synthetic hexapeptide which has a unique activity on melanocytes, keratinocytes and fibroblasts, inhibiting their three-way communication. Moreover, it inhibits the production of melanin, reduces the number of dendrites and has an antioxidant effect.

Telessence Telmeric™ soothes the Envirostress damage response activated by the TLR2 signalling pathway, alleviating the NF-kB response and, hence, relieving inflammation, which is also reduced by the action of miRNAs

V-4s™ protects our skin from the main four radicals. V-4s™ decreases the levels of reactive oxygen species (ROS) induced by H2O2 and ozone, scavenges sulfur (RSS) and nitril species (RNS), and protects against lipid-peroxidation-derived reactive carbonyl species (RCS).

Versillin™ boosts the fibrillin-versican-hyaluronan elastic-hydrated matrix, reinforcing the connective tissue of the dermis and the beauty columns (skin ligaments) to anchor and fasten the skin. The overall benefit is an increase in firmness and viscoelasticity to reposition the beauty columns into their original position.

Technology Plants as Biofactories

Anargy™ contains proteins that are able to nourish, protect and detoxify hair root helping to reactivate hair growth cycle for a redensifying and strengthening of hair locks. Naturally amplifies, extends, lifts and curls your eyelashes letting them bloom.

Col-Frag remastered™ acts as a building block and booster for collagen synthesis, and tightens the dermis and epidermis while preventing senescence. It revealed a synergistic effect and a superior efficacy to Ascorbyl Glucoside in reducing wrinkles, providing a facelift and enhancing skin brightness.

Epitensive™ contains plant-Epidermal Growth Factor (plant-EGF), a protein able to activate the ERK and AKT pathways. These paths are involved in protein synthesis and cellular regeneration to provide mature skin with the right extracellular matrix content and regenerative capacity lost with age.

Pureoxin™ contains plant-Thioredoxin-1 (plant-TRX-1), a multifunctional protein able to protect the skin from inflammaging and photoaging caused by ROS, MMP-9 and TNFα induced by radiation. Moreover, it can decrease the content of superficial melanin helping to lighten and illuminate skin tone.

Reneseed™ contains plant-Transforming Growth Factor Beta-2 (plant TGFβ2), the seed of youth of our skin, as it is implicated in the extracellular matrix protein synthesis and the production of epidermal lipids, improving the skin integrity and protection. It has a retinol and retinoic acid-like activity in terms of collagen I production efficacy.

Reneseed™ helps your skin to recover its own beauty that is sleeping inside with its broad-spectrum antiaging properties and pore size minimizer efficacy for night but also for day treatments.

Scelleye™ contains plant-Insulin-like Growth Factor-1 (plant-IGF1), a protein able to restore the activity of the skin basal layers, as well as to activate the proteasome and decrease carbonylation, for an effective clearance of damaged proteins.

Timlog™ is a plant-based human TIMP-2 which is an inhibitor of all MMPs. Additionally, it increases fibromodulin. Timlog™ acts as a guardian for skin’s dermochronology, repairing dermal solar scars redefining the past.

Wisegrade™ helps to regulate the amount of desired grey hair, in a natural non-damaging way. Wisegrade™ also provides antioxidant protection, enhances gloss.